Tumor necrosis factor-alpha in Patients with Pseudo exfoliation Syndrome
نویسندگان
چکیده
The aim of the present study was to determine the level of Tumor necrosis factor-alpha in aqueous humor and serum of patients with pseudo exfoliation syndrome. The materials and methods in this study, we measured the level of Tumor necrosis factor-alpha, in aqueous and serum of patients with pseudo exfoliation syndrome and compared the findings with healthy controls. The Results are Regarding Aqueous humor, the level of Tumor necrosis factor-alpha in PXS group was significantly higher than those of the control group (3.97 ±2.241 vs.2.54 ±0.713 pg/ml, P=0.02). The serum level of Tumor necrosis factor-alpha in PXS group was significantly higher than those of the control group (8.70±1.83 vs.7.03±1.85 pg/ml; p=0.001). In Conclusion the results suggest that level of Tumor necrosis factor-alpha rose in aqueous and serum of pseudo exfoliation syndrome.
منابع مشابه
Increased Tumor Necrosis Factor-alpha Expression as an Inflammatory Response Indicator and a Cancer Risk in Polycystic Ovarian Syndrome
Background: Polycystic Ovarian Syndrome (PCOS) is a pro-inflammatory condition that supports the development of metabolic aberration and ovarian dysfunction. Chronic inflammation and the increased levels of androgens in this group of patients and their impact on the immune system may increase the risk of developing malignancies, including ovarian cancer. Thus, we interacted ovarian tumor cells ...
متن کاملEndometriosis Classification and The Role of Tumor Necrosis Factor-Alpha Polymorphisms as A Therapeutic Target
In the recent original research published on International Journal of Fertility and Sterility the association between tumor necrosis factor-alpha (TNF-α) genetic polymorphisms and endometriosis in 150 Iranian patients suffered this disease. The authors notably found a lower frequency of TNF-α -863C/A allele A among the affected patients in comparison with healthy women, although this difference...
متن کاملEvaluation of relationship between the level of inflammatory cytokines Interleukin-10 and tumor necrosis factor-alpha with virologic response to treatment in patients with HIV
Background: Despite the considerable advances in acquired immunodeficiency syndrome (AIDS) treatment and management, finding the cure for this disease has been hindered by emerging challenges such as virus resistance and treatment failures. The purpose of this study is to compare the cytokine profiles of patients with successful treatment and patients with unsuccessful treatment to gain a bette...
متن کاملTumor necrosis factor alpha-308 gene polymorphism and pseudoexfoliation glaucoma
PURPOSE To investigate the possible association between tumor necrosis factor alpha (TNF-alpha)-308 G/A polymorphism and pseudoexfoliation (PEX) glaucoma. METHODS One hundred and ten Turkish PEX glaucoma patients and 110 healthy control subjects were enrolled in the study. All participants underwent a complete ophthalmic examination. TNF-alpha-308 was genotyped by polymerase chain reaction an...
متن کاملTumor necrosis factor- α, adiponectin and their ratio in gestational diabetes mellitus
Background: It has been suggested that inflammation might be implicated in the gestational diabetes mellitus (GDM) complications, including insulin resistance. The aims of the current study were to explore maternal circulating values of TNF-α, adiponectin and the adiponectin/TNF-α ratio in women with GDM compared with normal pregnancy and their relationships with metabolic syndrome ...
متن کامل